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CD34

CD34
Нинди таксонда бар H. sapiens[d][1]
Кодлаучы ген CD34[d][1]
Молекуляр функция transcription factor binding[d][2], sulfate binding[d][3] һәм связывание углеводов[d][4]
Күзәнәк компоненты цитоплазма[3][5], мембрана өлеше[d][3], мембрана[d][3][3][3], күзәнәк мембранасы[d][3][3][5][…], күзәнәк мембранасы өлеше[d][6], күзәнәк тышындагы өлкә[d][3], күзәнәк өслеге[d][3], basal plasma membrane[d][3][3], glomerular endothelium fenestra[d][3][3], apical plasma membrane[d][3][3], intercellular bridge[d][5], perinuclear region of cytoplasm[d][5], лизосома[3][3], наружная сторона клеточной мембраны[d][3][7][8][…] һәм периферия клетки[d][3]
Биологик процесс extracellular exosome assembly[d][9], stem cell proliferation[d][10], positive regulation of interleukin-10 production[d][11], движение клеток[d][10], negative regulation of blood coagulation[d][11], metanephric glomerular mesangial cell differentiation[d][12], paracrine signaling[d][9], hematopoietic stem cell proliferation[d][2], positive regulation of granulocyte colony-stimulating factor production[d][10][13], negative regulation of gene expression[d][14], positive regulation of angiogenesis[d][9][15], regulation of blood pressure[d][11], vascular wound healing[d][7], positive regulation of gene expression[d][10], glomerular filtration[d][7][3], negative regulation of nitric oxide biosynthetic process[d][11], агрегация клеток[d][3][3], endothelial cell proliferation[d][9], mesangial cell-matrix adhesion[d][3][3], тканевый гомеостаз[d][15], positive regulation of vasculogenesis[d][15], endothelium development[d][10], regulation of immune response[d][3], negative regulation of cellular response to heat[d][11], positive regulation of transforming growth factor beta production[d][11], glomerular endothelium development[d][16], negative regulation of tumor necrosis factor production[d][11], cell-matrix adhesion[d][17], пролиферация[d][3][3], positive regulation of odontogenesis[d][15], negative regulation of cellular response to hypoxia[d][11], leukocyte migration[d][3][3], передача сигнала[d][10], transdifferentiation[d][12], negative regulation of neuron death[d][11], cell-cell adhesion[d][4] һәм гемопоэз[d][14]
Изображение Gene Atlas
Схематик иллюстрациясе

CD34 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[18][19]

  1. ↑ 1,0 1,1 UniProt
  2. ↑ 2,0 2,1 Bassères D., Wilson N., Koschmieder S. et al. RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element // EMBO J. — NPG, 2011. — ISSN 0261-4189; 1460-2075 — doi:10.1038/EMBOJ.2011.285 — PMID:21873977
  3. ↑ 3,00 3,01 3,02 3,03 3,04 3,05 3,06 3,07 3,08 3,09 3,10 3,11 3,12 3,13 3,14 3,15 3,16 3,17 3,18 3,19 3,20 3,21 3,22 3,23 3,24 3,25 3,26 3,27 3,28 3,29 GOA
  4. ↑ 4,0 4,1 Kanda H., Tanaka T., Matsumoto M. et al. Endomucin, a sialomucin expressed in high endothelial venules, supports L-selectin-mediated rolling // Int. Immunol. — OUP, 2004. — ISSN 0953-8178; 1460-2377 — doi:10.1093/INTIMM/DXH128 — PMID:15249540
  5. ↑ 5,0 5,1 5,2 5,3 E Poblet, F Jimenez-Acosta, A Rocamora QBEND/10 (anti-CD34 antibody) in external root sheath cells and follicular tumors // Journal of Cutaneous Pathology — Wiley-Blackwell, 1994. — ISSN 0303-6987; 1600-0560 — doi:10.1111/J.1600-0560.1994.TB00264.X — PMID:7525669
  6. ↑ S Suster, C Fisher Immunoreactivity for the human hematopoietic progenitor cell antigen (CD34) in lipomatous tumors // Am. J. Surg. Pathol. — Lippincott Williams & Wilkins, 1997. — ISSN 0147-5185; 1532-0979 — doi:10.1097/00000478-199702000-00009 — PMID:9042286
  7. ↑ 7,0 7,1 7,2 Kwon O., Miller S., Li N. et al. Bone marrow-derived endothelial progenitor cells and endothelial cells may contribute to endothelial repair in the kidney immediately after ischemia-reperfusion // J. Histochem. Cytochem. — SAGE Publishing, 2010. — ISSN 0022-1554; 1551-5044 — doi:10.1369/JHC.2010.956011 — PMID:20354148
  8. ↑ R Häfer, A Voigt, B Gruhn et al. Neuroblastoma cells can express the hematopoietic progenitor cell antigen CD34 as detected at surface protein and mRNA level // J. Neuroimmunol. — Elsevier BV, 1999. — ISSN 0165-5728; 1872-8421 — doi:10.1016/S0165-5728(99)00030-2 — PMID:10337918
  9. ↑ 9,0 9,1 9,2 9,3 Sahoo S., Klychko E., Thorne T. et al. Exosomes from human CD34(+) stem cells mediate their proangiogenic paracrine activity // Circ. Res. — Lippincott Williams & Wilkins, 2011. — ISSN 0009-7330; 1524-4571 — doi:10.1161/CIRCRESAHA.111.253286 — PMID:21835908
  10. ↑ 10,0 10,1 10,2 10,3 10,4 10,5 Inoue T., Sata M., Hikichi Y. et al. Mobilization of CD34-positive bone marrow-derived cells after coronary stent implantation: impact on restenosis // Circulation — Lippincott Williams & Wilkins, 2007. — ISSN 0009-7322; 1524-4539 — doi:10.1161/CIRCULATIONAHA.106.621714 — PMID:17261663
  11. ↑ 11,0 11,1 11,2 11,3 11,4 11,5 11,6 11,7 11,8 Chen S., Chang F., Chang H. et al. Human umbilical cord blood-derived CD34+ cells cause attenuation of multiorgan dysfunction during experimental heatstroke // Shock — Lippincott Williams & Wilkins, 2007. — ISSN 1073-2322; 1540-0514 — doi:10.1097/01.SHK.0000248593.71388.40 — PMID:17505307
  12. ↑ 12,0 12,1 Onofrj M. C., T Fulgente, D Nobilio et al. Mapping of event-related potentials to auditory and visual odd-ball paradigms in controls // European Neurology / J. Bogousslavsky — Karger Publishers, 1991. — ISSN 0369-1519; 0014-3022; 1421-9913; 2571-7103 — doi:10.1159/000116682 — PMID:1868864
  13. ↑ AS P., MA W., JP M. et al. Mechanisms of immune suppression in patients with head and neck cancer: presence of CD34(+) cells which suppress immune functions within cancers that secrete granulocyte-macrophage colony-stimulating factor // Clin. Cancer Res. / K. Flaherty — American Association for Cancer Research, 1995. — ISSN 1078-0432; 1557-3265 — PMID:9815891
  14. ↑ 14,0 14,1 Huss R. Human adult CD34- progenitor cells functionally express the chemokine receptors CCR1, CCR4, CCR7, CXCR5, and CCR10 but not CXCR4 // Stem Cells and Development — Mary Ann Liebert, Inc., 2005. — ISSN 1547-3287; 1061-6128; 1557-8534 — doi:10.1089/SCD.2005.14.329 — PMID:15969628
  15. ↑ 15,0 15,1 15,2 15,3 O Trubiani, D Tripodi, Fratte T. D. et al. Human dental pulp vasculogenesis evaluated by CD34 antigen expression and morphological arrangement // J. Dent. Res. — SAGE Publishing, 2003. — ISSN 0022-0345; 1544-0591 — doi:10.1177/154405910308200916 — PMID:12939361
  16. ↑ Hosoya M., Kawasaki Y., Suzuki H. Development of glomerular endothelial cells, podocytes and mesangial cells in the human fetus and infant // Tohoku Journal of Experimental Medicine — Tohoku University, 2007. — 10 p. — ISSN 0040-8727; 1349-3329 — doi:10.1620/TJEM.212.81 — PMID:17464107
  17. ↑ GOA
  18. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
  19. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

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